Van 't Hoff Institute for Molecular Sciences University of Amsterdam
In collaboration with researchers at VU Amsterdam, our group members Carlo Bigiotti, Ioana Ilie and Jocelyne Vreede have published an article in ChemBioChem titled Binding Dynamics of a Stapled Peptide Targeting the Transcription Factor NF−Y. In this paper, they investigate how truncated stapled α-helical peptides interact with the transcription factor Nuclear Factor-Y. Via molecular dynamics […]
Read moreTogether with HIMS Vibrational Spectroscopy, Ioana has published a paper about how water guides the assembly of collagen, the building block of all humans. Check out the highlight by HIMS and the article. Congrats, Ioana!
Read moreDr. Hannah Jonas has successfully defended her dissertation titled Colloidal patchy particle architectures: Simulations of accurate models in and out of equilibrium. She was promoted by Prof. Peter Bolhuis from HIMS and Prof. Peter Schall from IoP. In her thesis, she used patchy colloidal particles interacting via critical Casimir interactions as mesoscopic analogues for molecular, […]
Read moreDaria and Ioana have published a Highlight in ChemComm titled Unlocking novel therapies: cyclic peptide design for amyloidogenic targets through synergies of experiments, simulations, and machine learning. From a computational perspecrive, they review the latest advancements in cyclic peptide design against amyloidogenic targets in light of recent advancements and potential of machine learning. They discuss […]
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