Dr Jocelyne Vreede of the Computational Chemistry group at the Van ‘t Hoff Institute for Molecular Sciences has received an NWO KLEIN-2 grant for a four-year project investigating how the shape and compactness of DNA affect the expression of genes. In cooperation with Prof. Willem Kegel, professor of Self-organizing Systems at Utrecht University, experimental, theoretical and computational approaches will be developed to provide quantitative and detailed insights into this as of yet unknown aspect of DNA transcription.
https://hims.uva.nl/content/news/2020/03/how-does-the-accessibility-of-dna-affect-the-expression-of-genes.html?origin=ZBsmRfebSyq59D2IosWhGQ